Low PAPP‐A: what are the clinical implications?
نویسندگان
چکیده
Ultrasound and pulsed Doppler can assist in confirming impaired placentation looking at fetal biometry and umbilical artery Dopplers. The authors recommend confirmation of fetal wellbeing at 28-30 weeks with a PAPP-A level below the first centile.
منابع مشابه
Relationship between Low PAPP-A Levels and Preterm Delivery
Background and purpose: Preterm birth is the one that occurs before 37 weeks of pregnancy. Pregnancy-associated plasma protein A (PAPP-A) is one of the main elements in screening test for Down syndrome, carried out at 11-14 weeks of gestational age. The aim of this study was to determine the relationship between low PAPP-A levels and preterm delivery. Materials and methods: A descriptive-analy...
متن کاملLow pregnancy-associated plasma protein A level in the first trimester.
OBJECTIVE To review the recent evidence behind the association of low levels (ie, below the fifth percentile) of pregnancy-associated plasma protein A (PAPP-A) with adverse perinatal outcomes and to integrate new findings with the recommendations made by the Society of Obstetricians and Gynaecologists of Canada in 2008. QUALITY OF EVIDENCE A review of recently published articles revealed that...
متن کاملزایمان زودرس و غلظت پایین پروتیین پلاسمایی A وابسته به حاملگی در سه ماهه اول بارداری
Background: Previous investigations have shown that pregnancy-associated plasma protein-A (PAPP-A) levels are associated with adverse pregnancy outcomes including intrauterine growth restriction (IUGR) fetuses as well as preterm delivery. The aim of this study was to determine the rate of preterm delivery in women with low PAPP-A and at intermediate risk for chromosomal abnormalities in the fir...
متن کاملبررسی ارتباط طول سری دمی جنین و پروتیین A پلاسمایی مرتبط با حاملگی اندازه‌گیری‌شده در سه‌ماهه اول حاملگی با وزن تولد جنین
Background: Recent studies have suggested that impaired fetal growth are indicators that may be present in the first trimester. The aim of this study was to investigate the relationship between crown-rump length (CRL) and pregnancy associated plasma protein-A (PAPP-A) measurements in first trimester for low birth weight (LBW).Methods: This prospective cohort study were on 120 pregnant women in ...
متن کاملارتباط اختلال رشد درون رحمی با سطح هورمون‌های گونادوتروپین جفتی انسانی و پروتئین پلاسمایی وابسته به حاملگی
Background & Aim : Intrauterine growth retardation (IUGR) and preterm birth are major determinants of prenatal morbidity and mortality. Standard diagnostic methods like ultrasound are accurate, but they cannot be employed as the screening tools. Lately, it is proposed that there might be an association between IUGR and placental dysfunction so its hormones such as human chorionic gonadotropin...
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